منابع مشابه
Decrease of Fibulin-3 in Hepatocellular Carcinoma Indicates Poor Prognosis
Fibulin-3, originally identified in senescent and Werner syndrome fibroblasts, has been implicated in cell morphology, growth, adhesion and motility. Fibulin-3 exhibits both antitumor and oncogenic activities towards human cancers; however, the role of Fibulin-3 in hepatocellular carcinoma (HCC) remains elusive. In this study, we showed that both the mRNA and protein levels of Fibulin-3 were re...
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متن کاملCardiac Fibrosis
Heart failure, the clinical manifestation of numerous forms of cardiovascular disease, is a devastating disorder characterized by interstitial fibrosis, chamber remodeling, and reduced ventricular compliance. Heart disease remains the predominant cause of mortality in the United States, accounting for nearly 800 000 deaths per year. Furthermore, it presents a considerable economic burden, with ...
متن کاملCardiac Involvement in Mild Cystic Fibrosis Lung Involvement Assessed by Tissue‐Doppler Echocardiography
Background:Cystic Fibrosis (CF) is a systemic disease affecting extra pulmonary dysfunction as a result of CF-related lung disease. Because of lack of enough studies in this field and utilization of TDE in this field, we aimed to evaluate t...
متن کاملCardiac dysfunction is attenuated by ginkgolide B via reducing oxidative stress and fibrosis in diabetic rats
Objective(s): Diabetic cardiomyopathy is a leading factor of high morbidity and mortality in diabetic patients. Our previous results revealed that ginkgolide B alleviates endothelial dysfunction in diabetic rats. This study aimed to investigate the effect of ginkgolide B on cardiac dysfunction and its mechanism in diabetic rats.Materials and Methods:<...
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ژورنال
عنوان ژورنال: Heart, Lung and Circulation
سال: 2017
ISSN: 1443-9506
DOI: 10.1016/j.hlc.2017.06.207